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SPRO

Spero Therapeutics (SPRO) stock: insider trades, news & valuation

Net selling
Close · Oct 9, 2026 $1.20 +5.3% on the day -49.2% over 12 months 52-week range $1.11 – $2.98

Share price and insider trades

SPRO closeInsider buyInsider sale
123NovDecJan 2026FebMarAprMayJunJulAugSepOctSold $7,775 on 2026-02-04 · Timothy KeutzerSold $51,839 on 2026-02-03 · Timothy KeutzerSold $63,352 on 2026-05-04 · Esther RajaveluSold $82,133 on 2026-02-02 · Esther Rajavelu, Timothy KeutzerSold $95,440 on 2025-11-07 · Esther RajaveluSold $251,503 on 2026-02-06 · Esther Rajavelu, Timothy Keutzer
Bought, 12 months$0
Sold, 12 months$552K
Insiders buying0
Insiders selling2

Spero Therapeutics insider trading at a glance (Oct 9, 2026): in the past 12 months, 0 insiders bought $0 and 2 sold $552K of SPRO stock on the open market.

SPRO insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q4 2025: $95K sold (1 trades)Q4 2025Q1 2026: $393K sold (7 trades)Q1 2026Q2 2026: $63K sold (1 trades)Q2 2026Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0—0
Q2 2026—0$63K1
Q1 2026—0$393K7
Q4 2025—0$95K1

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day0.6×Last 5 sessions
Insiders' paper profit—On all tracked purchases —

Summary

Over the past 12 months, 0 Spero Therapeutics, Inc. insiders reported open-market purchases totaling $0, while 2 insiders reported sales totaling $552K. 0 of 9 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
May 6SEC Esther RajaveluSee Remarks Sell 25,240986,851 held (−2%) $2.51 $63K -52.2% —
Feb 9SEC Esther RajaveluSee Remarks Sell 50,8161,012,091 held (−5%) $2.36 $120K -49.2% —
Feb 9SEC Esther RajaveluSee Remarks Sell 37,1011,062,907 held (−3%) $2.36 $88K -49.2% —
Feb 9SEC Timothy KeutzerCOO Sell 18,652742,506 held (−2%) $2.36 $44K -49.2% —
Feb 5SEC Timothy KeutzerCOO Sell 24,224764,629 held (−3%) $2.14 $52K -43.9% —
Feb 5SEC Timothy KeutzerCOO Sell 18,891788,853 held (−2%) $2.20 $42K -45.5% —
Feb 5SEC Timothy KeutzerCOO Sell 3,471761,158 held (−0%) $2.24 $8K -46.4% —
Feb 4SEC Esther RajaveluSee Remarks Sell 18,4421,100,008 held (−2%) $2.20 $41K -45.5% —
Nov 12SEC Esther RajaveluSee Remarks Sell 40,270869,450 held (−4%) $2.37 $95K -49.4% —

Insiders at Spero Therapeutics, Inc.

InsiderBoughtSoldLast filingScore
Esther RajaveluSee Remarks — $407K May 6, 2026 —
Timothy KeutzerCOO — $145K Feb 9, 2026 —

SPRO stock: common questions

Are Spero Therapeutics, Inc. insiders buying SPRO stock?

In the past 12 months, 0 insiders reported open-market purchases of SPRO worth $0.

Are Spero Therapeutics, Inc. insiders selling SPRO stock?

2 insiders reported sales worth $552K over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is SPRO's 52-week range?

Over the past year SPRO has traded between $1.11 and $2.98. It last closed at $1.20 on Oct 9, 2026.