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SION

Sionna Therapeutics (SION) stock: insider trades, news & valuation

Heavy selling
Close · Oct 9, 2026 $4.90 +0.0% on the day -82.7% over 12 months 52-week range $4.50 – $51.04

Share price and insider trades

SION closeInsider buyInsider sale
0204060NovDecJan 2026FebMarAprMayJunJulAugSepOctSold $8,898 on 2025-12-18 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $8,987 on 2026-05-27 · Orbimed Advisors Llc, Peter A. ThompsonSold $18,150 on 2025-10-14 · Bruce BoothSold $77,858 on 2025-12-19 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $80,100 on 2025-12-17 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $142,368 on 2025-11-26 · Orbimed Advisors Llc, Peter A. ThompsonSold $168,475 on 2026-02-02 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $205,975 on 2025-11-20 · Peter KolchinskySold $262,490 on 2026-04-18 · Orbimed Advisors Llc, Peter A. ThompsonSold $273,904 on 2025-11-18 · Ra Capital Management, L.P.Sold $347,065 on 2026-03-05 · Jennifer FitzpatrickSold $415,330 on 2025-12-05 · Jennifer FitzpatrickSold $446,900 on 2026-07-06 · Jennifer FitzpatrickSold $606,735 on 2025-10-10 · Bruce BoothSold $994,728 on 2025-11-21 · Peter KolchinskySold $1,060,588 on 2025-11-25 · Orbimed Advisors Llc, Peter A. ThompsonSold $1,769,101 on 2025-10-13 · Bruce BoothSold $1,796,611 on 2025-10-20 · Bruce BoothSold $1,898,173 on 2025-11-19 · Ra Capital Management, L.P.Sold $1,978,323 on 2025-10-17 · Bruce BoothSold $2,478,104 on 2025-10-28 · Ra Capital Nexus Fund Iii, L.P.Sold $2,591,257 on 2026-02-03 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $2,972,020 on 2025-12-24 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $3,328,081 on 2025-11-17 · Ra Capital Management, L.P.Sold $4,005,448 on 2025-10-15 · Bruce Booth, Michael CloonanSold $4,256,402 on 2026-04-14 · Orbimed Advisors Llc, Peter A. ThompsonSold $4,331,274 on 2026-05-07 · Orbimed Advisors Llc, Peter A. ThompsonSold $4,682,196 on 2026-04-17 · Orbimed Advisors Llc, Peter A. ThompsonSold $5,328,826 on 2026-05-08 · Orbimed Advisors Llc, Peter A. ThompsonSold $5,804,646 on 2025-10-16 · Bruce Booth, Michael CloonanSold $6,660,244 on 2025-10-21 · Bruce Booth, Michael CloonanSold $7,708,563 on 2026-07-07 · Orbimed Capital Gp Viii Llc, Peter A. ThompsonSold $8,425,454 on 2025-11-24 · Orbimed Advisors Llc, Peter A. ThompsonSold $10,000,000 on 2026-01-22 · Jon WinkelriedSold $10,541,804 on 2026-06-30 · Orbimed Advisors Llc, Peter A. ThompsonSold $12,284,500 on 2025-10-24 · Ra Capital Nexus Fund Iii, L.P.Sold $17,068,029 on 2026-05-11 · Orbimed Advisors Llc, Peter A. ThompsonSold $20,575,836 on 2026-04-16 · Orbimed Advisors Llc, Peter A. ThompsonSold $21,057,849 on 2026-04-15 · Orbimed Advisors Llc, Peter A. ThompsonSold $21,835,018 on 2026-09-17 · Ra Capital Management, L.P.
Bought, 12 months$0
Sold, 12 months$188M
Insiders buying0
Insiders selling10

Sionna Therapeutics insider trading at a glance (Oct 9, 2026): in the past 12 months, 0 insiders bought $0 and 10 sold $188M of SION stock on the open market.

SION insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q3 2025: $2.4M sold (4 trades)Q3 2025Q4 2025: $58.8M sold (112 trades)Q4 2025Q1 2026: $13.1M sold (6 trades)Q1 2026Q2 2026: $88.1M sold (20 trades)Q2 2026Q3 2026: $30.0M sold (5 trades)Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0$30.0M5
Q2 2026—0$88.1M20
Q1 2026—0$13.1M6
Q4 2025—0$58.8M112
Q3 2025—0$2.4M4

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day0.4×Last 5 sessions
Insiders' paper profit—On all tracked purchases —

Summary

Over the past 12 months, 0 Sionna Therapeutics, Inc. insiders reported open-market purchases totaling $0, while 10 insiders reported sales totaling $188M. Among insiders with enough purchase history to measure, Peter Kolchinsky (Director) has the highest Insider Score at 99. 100 of 147 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Sep 21SEC Ra Capital Management, L.P.Director Sell 3,415,0113,482,612 held (−50%) $6.32 $21.6M -22.5% 92
Sep 21SEC Ra Capital Management, L.P.Director Sell 33,8003,448,812 held (−1%) $7.46 $252K -34.3% 92
Jul 9SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 85,9182,469,959 held (−3%) $44.86 $3.9M -89.1% —
Jul 9SEC Peter A. ThompsonDirector Sell Plan 85,9182,469,959 held (−3%) $44.86 $3.9M -89.1% —
Jul 7SEC Jennifer FitzpatrickGeneral Counsel Sell Plan 10,250 $43.60 $447K -88.8% —
Jul 2SEC Orbimed Advisors LlcDirector Sell Plan 115,8442,555,877 held (−4%) $45.50 $5.3M -89.2% —
Jul 2SEC Peter A. ThompsonDirector Sell Plan 115,8442,555,877 held (−4%) $45.50 $5.3M -89.2% —
May 29SEC Peter A. ThompsonDirector Sell Plan 1012,671,721 held (−0%) $44.49 $4K -89.0% —
May 29SEC Orbimed Advisors LlcDirector Sell Plan 1012,671,721 held (−0%) $44.49 $4K -89.0% —
May 11SEC Peter A. ThompsonDirector Sell Plan 184,6392,671,822 held (−6%) $46.22 $8.5M -89.4% —
May 11SEC Orbimed Advisors LlcDirector Sell Plan 184,6392,671,822 held (−6%) $46.22 $8.5M -89.4% —
May 11SEC Peter A. ThompsonDirector Sell Plan 59,7672,856,461 held (−2%) $44.58 $2.7M -89.0% —
May 11SEC Orbimed Advisors LlcDirector Sell Plan 59,7672,856,461 held (−2%) $44.58 $2.7M -89.0% —
May 11SEC Peter A. ThompsonDirector Sell Plan 48,5462,916,228 held (−2%) $44.61 $2.2M -89.0% —
May 11SEC Orbimed Advisors LlcDirector Sell Plan 48,5462,916,228 held (−2%) $44.61 $2.2M -89.0% —
Apr 21SEC Orbimed Advisors LlcDirector Sell Plan 52,3972,967,722 held (−2%) $44.68 $2.3M -89.0% —
Apr 21SEC Peter A. ThompsonDirector Sell Plan 52,3972,967,722 held (−2%) $44.68 $2.3M -89.0% —
Apr 21SEC Orbimed Advisors LlcDirector Sell Plan 2,9482,964,774 held (−0%) $44.52 $131K -89.0% —
Apr 21SEC Peter A. ThompsonDirector Sell Plan 2,9482,964,774 held (−0%) $44.52 $131K -89.0% —
Apr 16SEC Orbimed Advisors LlcDirector Sell Plan 235,8633,247,025 held (−7%) $44.64 $10.5M -89.0% —
Apr 16SEC Peter A. ThompsonDirector Sell Plan 235,8633,247,025 held (−7%) $44.64 $10.5M -89.0% —
Apr 16SEC Orbimed Advisors LlcDirector Sell Plan 226,9063,020,119 held (−7%) $45.34 $10.3M -89.2% —
Apr 16SEC Peter A. ThompsonDirector Sell Plan 226,9063,020,119 held (−7%) $45.34 $10.3M -89.2% —
Apr 16SEC Orbimed Advisors LlcDirector Sell Plan 47,8143,482,888 held (−1%) $44.51 $2.1M -89.0% —
Apr 16SEC Peter A. ThompsonDirector Sell Plan 47,8143,482,888 held (−1%) $44.51 $2.1M -89.0% —
Mar 6SEC Jennifer FitzpatrickGeneral Counsel Sell Plan 10,250 $33.86 $347K -85.5% —
Feb 4SEC Peter A. ThompsonDirector Sell Plan 29,0633,530,702 held (−1%) $44.58 $1.3M -89.0% —
Feb 4SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 29,0633,530,702 held (−1%) $44.58 $1.3M -89.0% —
Feb 4SEC Peter A. ThompsonDirector Sell Plan 1,8903,559,765 held (−0%) $44.57 $84K -89.0% —
Feb 4SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 1,8903,559,765 held (−0%) $44.57 $84K -89.0% —
Jan 26SEC Jon Winkelried10% Owner Sell 250,0006,494,962 held (−4%) $40.00 $10.0M -87.8% —
Dec 29SEC Peter A. ThompsonDirector Sell Plan 33,3563,561,655 held (−1%) $44.55 $1.5M -89.0% —
Dec 29SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 33,3563,561,655 held (−1%) $44.55 $1.5M -89.0% —
Dec 19SEC Peter A. ThompsonDirector Sell Plan 9003,595,986 held (−0%) $44.50 $40K -89.0% —
Dec 19SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 9003,595,986 held (−0%) $44.50 $40K -89.0% —
Dec 19SEC Peter A. ThompsonDirector Sell Plan 8753,595,011 held (−0%) $44.49 $39K -89.0% —
Dec 19SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 8753,595,011 held (−0%) $44.49 $39K -89.0% —
Dec 19SEC Peter A. ThompsonDirector Sell Plan 1003,595,886 held (−0%) $44.49 $4K -89.0% —
Dec 19SEC Orbimed Capital Gp Viii LlcDirector Sell Plan 1003,595,886 held (−0%) $44.49 $4K -89.0% —
Dec 9SEC Jennifer FitzpatrickGeneral Counsel Sell Plan 10,250 $40.52 $415K -87.9% —
Nov 26SEC Orbimed Advisors LlcDirector Sell Plan 94,5833,610,376 held (−3%) $44.54 $4.2M -89.0% —
Nov 26SEC Peter A. ThompsonDirector Sell Plan 94,5833,610,376 held (−3%) $44.54 $4.2M -89.0% —
Nov 26SEC Orbimed Advisors LlcDirector Sell Plan 11,8903,598,486 held (−0%) $44.60 $530K -89.0% —
Nov 26SEC Peter A. ThompsonDirector Sell Plan 11,8903,598,486 held (−0%) $44.60 $530K -89.0% —
Nov 26SEC Orbimed Advisors LlcDirector Sell Plan 1,6003,596,886 held (−0%) $44.49 $71K -89.0% —
Nov 26SEC Peter A. ThompsonDirector Sell Plan 1,6003,596,886 held (−0%) $44.49 $71K -89.0% —
Nov 24SEC Peter KolchinskyDirector Sell 9,924650,307 held (−2%) $39.50 $392K -87.6% 99
Nov 24SEC Peter KolchinskyDirector Sell 7,609159,033 held (−5%) $39.50 $301K -87.6% 99
Nov 24SEC Peter KolchinskyDirector Sell 6,4402,198,082 held (−0%) $39.50 $254K -87.6% 99
Nov 24SEC Peter KolchinskyDirector Sell 1,235661,019 held (−0%) $39.89 $49K -87.7% 99
Nov 24SEC Peter KolchinskyDirector Sell 1,2106,897,623 held (−0%) $39.50 $48K -87.6% 99
Nov 24SEC Peter KolchinskyDirector Sell 947167,246 held (−1%) $39.89 $38K -87.7% 99
Nov 24SEC Peter KolchinskyDirector Sell 8012,205,034 held (−0%) $39.89 $32K -87.7% 99
Nov 24SEC Peter KolchinskyDirector Sell 788660,231 held (−0%) $40.50 $32K -87.9% 99
Nov 24SEC Peter KolchinskyDirector Sell 604166,642 held (−0%) $40.50 $24K -87.9% 99
Nov 24SEC Peter KolchinskyDirector Sell 5122,204,522 held (−0%) $40.50 $21K -87.9% 99
Nov 24SEC Peter KolchinskyDirector Sell 1506,898,929 held (−0%) $39.89 $6K -87.7% 99
Nov 24SEC Peter KolchinskyDirector Sell 966,898,833 held (−0%) $40.50 $4K -87.9% 99
Nov 19SEC Ra Capital Management, L.P.Director Sell 18,684662,266 held (−3%) $40.01 $748K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 17,913698,075 held (−3%) $40.20 $720K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 13,964684,111 held (−2%) $41.05 $573K -88.1% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 14,325168,202 held (−8%) $40.01 $573K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 13,734195,657 held (−7%) $40.20 $552K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 12,1262,205,843 held (−1%) $40.01 $485K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 11,6262,229,082 held (−1%) $40.20 $467K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 10,707184,950 held (−5%) $41.05 $440K -88.1% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 9,0632,220,019 held (−0%) $41.05 $372K -88.1% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 2,728680,950 held (−0%) $39.57 $108K -87.6% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 2,2766,899,081 held (−0%) $40.01 $91K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 2,1826,903,443 held (−0%) $40.20 $88K -87.8% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 2,092182,527 held (−1%) $39.57 $83K -87.6% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 1,7702,217,969 held (−0%) $39.57 $70K -87.6% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 1,7016,901,742 held (−0%) $41.05 $70K -88.1% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 433683,678 held (−0%) $42.10 $18K -88.4% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 331184,619 held (−0%) $42.10 $14K -88.4% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 3326,901,357 held (−0%) $39.57 $13K -87.6% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 2802,219,739 held (−0%) $42.10 $12K -88.4% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 536,901,689 held (−0%) $42.10 $2K -88.4% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 12662,254 held (−0%) $40.61 $487 -87.9% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 9168,193 held (−0%) $40.61 $365 -87.9% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 82,205,835 held (−0%) $40.61 $325 -87.9% 92
Nov 19SEC Ra Capital Management, L.P.Director Sell 26,899,079 held (−0%) $40.61 $81 -87.9% 92
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 122,271747,380 held (−14%) $39.50 $4.8M -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 107,941219,867 held (−33%) $39.50 $4.3M -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 66,6722,257,826 held (−3%) $39.50 $2.6M -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 31,392715,988 held (−4%) $39.58 $1.2M -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 17,1182,240,708 held (−1%) $39.58 $678K -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 14,1166,909,249 held (−0%) $39.50 $558K -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 10,476209,391 held (−5%) $39.58 $415K -87.6% 85
Oct 28SEC Ra Capital Nexus Fund Iii, L.P.Director Sell 3,6246,905,625 held (−0%) $39.58 $143K -87.6% 85
Oct 22SEC Michael CloonanCEO, President Sell Plan 33,532547,343 held (−6%) $37.31 $1.3M -86.9% —
Oct 22SEC Michael CloonanCEO, President Sell Plan 30,049547,343 held (−5%) $35.63 $1.1M -86.2% —
Oct 22SEC Michael CloonanCEO, President Sell Plan 22,895547,343 held (−4%) $36.60 $838K -86.6% —
Oct 22SEC Michael CloonanCEO, President Sell Plan 13,324547,343 held (−2%) $34.44 $459K -85.8% —
Oct 21SEC Bruce BoothDirector Sell Plan 25,3272,309,118 held (−1%) $35.69 $904K -86.3% —
Oct 21SEC Bruce BoothDirector Sell Plan 22,3392,360,156 held (−1%) $32.69 $730K -85.0% —
Oct 21SEC Bruce BoothDirector Sell Plan 19,9482,340,208 held (−1%) $33.87 $676K -85.5% —
Oct 21SEC Bruce BoothDirector Sell Plan 5,7632,334,445 held (−0%) $34.91 $201K -86.0% —
Oct 21SEC Bruce BoothDirector Sell Plan 5,316686,584 held (−1%) $35.69 $190K -86.3% —
Oct 21SEC Bruce BoothDirector Sell Plan 4,688697,297 held (−1%) $32.69 $153K -85.0% —
Oct 21SEC Bruce BoothDirector Sell Plan 4,187693,110 held (−1%) $33.87 $142K -85.5% —
Oct 21SEC Bruce BoothDirector Sell Plan 1,210691,900 held (−0%) $34.91 $42K -86.0% —
Oct 21SEC Bruce BoothDirector Sell Plan 832,309,035 held (−0%) $36.42 $3K -86.5% —
Oct 21SEC Bruce BoothDirector Sell Plan 17686,567 held (−0%) $36.42 $619 -86.5% —
Oct 20SEC Bruce BoothDirector Sell Plan 73,2962,492,176 held (−3%) $32.84 $2.4M -85.1% —
Oct 20SEC Bruce BoothDirector Sell Plan 45,1172,565,472 held (−2%) $31.69 $1.4M -84.5% —
Oct 20SEC Bruce BoothDirector Sell Plan 28,8212,450,467 held (−1%) $32.10 $925K -84.7% —
Oct 20SEC Bruce BoothDirector Sell Plan 25,7882,382,495 held (−1%) $32.33 $834K -84.8% —
Oct 20SEC Bruce BoothDirector Sell Plan 21,4512,429,016 held (−1%) $32.71 $702K -85.0% —
Oct 20SEC Bruce BoothDirector Sell Plan 20,4852,408,283 held (−1%) $31.79 $651K -84.6% —
Oct 20SEC Bruce BoothDirector Sell Plan 15,384725,006 held (−2%) $32.84 $505K -85.1% —
Oct 20SEC Bruce BoothDirector Sell Plan 12,8882,479,288 held (−1%) $33.38 $430K -85.3% —
Oct 20SEC Bruce BoothDirector Sell Plan 9,470740,390 held (−1%) $31.69 $300K -84.5% —
Oct 20SEC Bruce BoothDirector Sell Plan 8,5962,610,589 held (−0%) $30.15 $259K -83.7% —
Oct 20SEC Bruce BoothDirector Sell Plan 6,049716,252 held (−1%) $32.10 $194K -84.7% —
Oct 20SEC Bruce BoothDirector Sell Plan 5,412701,985 held (−1%) $32.33 $175K -84.8% —
Oct 20SEC Bruce BoothDirector Sell Plan 4,503711,749 held (−1%) $32.71 $147K -85.0% —
Oct 20SEC Bruce BoothDirector Sell Plan 4,300707,397 held (−1%) $31.79 $137K -84.6% —
Oct 20SEC Bruce BoothDirector Sell Plan 2,705722,301 held (−0%) $33.38 $90K -85.3% —
Oct 20SEC Bruce BoothDirector Sell Plan 1,804749,860 held (−0%) $30.15 $54K -83.7% —
Oct 20SEC Bruce BoothDirector Sell Plan 2482,428,768 held (−0%) $33.47 $8K -85.4% —
Oct 20SEC Bruce BoothDirector Sell Plan 52711,697 held (−0%) $33.47 $2K -85.4% —
Oct 17SEC Michael CloonanCEO, President Sell Plan 14,775547,343 held (−3%) $31.11 $460K -84.2% —
Oct 17SEC Michael CloonanCEO, President Sell Plan 10,225547,343 held (−2%) $31.46 $322K -84.4% —
Oct 17SEC Michael CloonanCEO, President Sell Plan 200547,343 held (−0%) $34.00 $7K -85.6% —
Oct 15SEC Bruce BoothDirector Sell Plan 65,7262,649,217 held (−2%) $30.37 $2.0M -83.9% —
Oct 15SEC Bruce BoothDirector Sell Plan 44,0482,719,526 held (−2%) $30.32 $1.3M -83.8% —
Oct 15SEC Bruce BoothDirector Sell Plan 30,0322,619,185 held (−1%) $31.12 $935K -84.3% —
Oct 15SEC Bruce BoothDirector Sell Plan 16,7272,763,574 held (−1%) $29.98 $501K -83.7% —
Oct 15SEC Bruce BoothDirector Sell Plan 13,795757,967 held (−2%) $30.37 $419K -83.9% —
Oct 15SEC Bruce BoothDirector Sell Plan 9,245772,724 held (−1%) $30.32 $280K -83.8% —
Oct 15SEC Bruce BoothDirector Sell Plan 6,303751,664 held (−1%) $31.12 $196K -84.3% —
Oct 15SEC Bruce BoothDirector Sell Plan 4,0822,715,444 held (−0%) $31.03 $127K -84.2% —
Oct 15SEC Bruce BoothDirector Sell Plan 3,511781,969 held (−0%) $29.98 $105K -83.7% —
Oct 15SEC Bruce BoothDirector Sell Plan 857771,867 held (−0%) $31.03 $27K -84.2% —
Oct 15SEC Bruce BoothDirector Sell Plan 5012,714,943 held (−0%) $29.95 $15K -83.6% —
Oct 15SEC Bruce BoothDirector Sell Plan 105771,762 held (−0%) $29.95 $3K -83.6% —
Oct 7SEC Bruce BoothDirector Sell Plan 31,1982,790,054 held (−1%) $30.00 $936K -83.7% —
Oct 7SEC Bruce BoothDirector Sell Plan 9,7532,780,301 held (−0%) $29.95 $292K -83.6% —
Oct 7SEC Bruce BoothDirector Sell Plan 6,548787,527 held (−1%) $30.00 $196K -83.7% —
Oct 7SEC Bruce BoothDirector Sell Plan 2,047785,480 held (−0%) $29.95 $61K -83.6% —
Oct 1SEC Bruce BoothDirector Sell Plan 54,6372,831,656 held (−2%) $30.09 $1.6M -83.7% —
Oct 1SEC Bruce BoothDirector Sell Plan 11,468796,259 held (−1%) $30.09 $345K -83.7% —
Oct 1SEC Bruce BoothDirector Sell Plan 10,2392,821,417 held (−0%) $30.06 $308K -83.7% —
Oct 1SEC Bruce BoothDirector Sell Plan 2,149794,110 held (−0%) $30.06 $65K -83.7% —
Oct 1SEC Bruce BoothDirector Sell Plan 1652,821,252 held (−0%) $29.95 $5K -83.6% —
Oct 1SEC Bruce BoothDirector Sell Plan 35794,075 held (−0%) $29.95 $1K -83.6% —

Insiders at Sionna Therapeutics, Inc.

InsiderBoughtSoldLast filingScore
Peter A. ThompsonDirector — $55.7M Jul 9, 2026 —
Orbimed Advisors LlcDirector — $48.9M Jul 2, 2026 —
Ra Capital Management, L.P.Director — $27.3M Sep 21, 2026 92
Bruce BoothDirector — $22.1M Oct 21, 2025 —
Ra Capital Nexus Fund Iii, L.P.Director — $14.8M Oct 28, 2025 85
Jon Winkelried10% Owner — $10.0M Jan 26, 2026 —
Orbimed Capital Gp Viii LlcDirector — $6.8M Jul 9, 2026 —
Michael CloonanCEO, President — $4.4M Oct 22, 2025 —
Jennifer FitzpatrickGeneral Counsel — $1.2M Jul 7, 2026 —
Peter KolchinskyDirector — $1.2M Nov 24, 2025 99

SION stock: common questions

Are Sionna Therapeutics, Inc. insiders buying SION stock?

In the past 12 months, 0 insiders reported open-market purchases of SION worth $0.

Are Sionna Therapeutics, Inc. insiders selling SION stock?

10 insiders reported sales worth $188M over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is SION's 52-week range?

Over the past year SION has traded between $4.50 and $51.04. It last closed at $4.90 on Oct 9, 2026.