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Insider tapeFilings through Fri, Oct 9
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OPK

OPKO HEALTH (OPK) stock: insider trades, news & valuation

Strong buying
Close · Oct 9, 2026 $1.38 +0.7% on the day -11.5% over 12 months 52-week range $1.10 – $1.73

Share price and insider trades

OPK closeInsider buyInsider sale
1.001.201.401.601.80NovDecJan 2026FebMarAprMayJunJulAugSepOctBought $11,400 on 2026-03-20 · John A PaganelliBought $213,000 on 2025-10-31 · Phillip Md Et Al FrostBought $680,795 on 2025-11-18 · Frost Gamma Investments TrustBought $760,572 on 2025-11-19 · Frost Gamma Investments TrustBought $770,219 on 2025-11-21 · Frost Gamma Investments TrustBought $772,381 on 2025-11-20 · Frost Gamma Investments Trust
Bought, 12 months$3.2M
Sold, 12 months$0
Insiders buying3
Insiders selling0

OPKO HEALTH insider trading at a glance (Oct 9, 2026): in the past 12 months, 3 insiders bought $3.2M and 0 sold $0 of OPK stock on the open market.

OPK insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q4 2025: $3.2M bought (33 trades)$3.2MQ4 2025Q1 2026: $11K bought (1 trades)$11KQ1 2026Q2 2026Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0—0
Q2 2026—0—0
Q1 2026$11K1—0
Q4 2025$3.2M33—0

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day0.6×Last 5 sessions
Insiders' paper profit+$150KOn all tracked purchases +4.7%

Summary

Over the past 12 months, 3 OPKO HEALTH, INC. insiders reported open-market purchases totaling $3.2M, while 0 insiders reported sales totaling $0. Among insiders with enough purchase history to measure, Phillip Md Et Al Frost (CEO, Chair) has the highest Insider Score at 84.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Mar 20SEC John A PaganelliDirector Buy 10,000394,340 held (+3%) $1.14 $11K +21.1% —
Nov 21SEC Frost Gamma Investments Trust10% Owner Buy 192,870216,706,448 held (+0%) $1.34 $258K +3.0% 27
Nov 21SEC Frost Gamma Investments Trust10% Owner Buy 191,490216,513,578 held (+0%) $1.33 $255K +3.8% 27
Nov 21SEC Frost Gamma Investments Trust10% Owner Buy 102,371216,228,819 held (+0%) $1.30 $133K +6.2% 27
Nov 21SEC Frost Gamma Investments Trust10% Owner Buy 89,375216,322,088 held (+0%) $1.33 $119K +3.8% 27
Nov 21SEC Frost Gamma Investments Trust10% Owner Buy 3,894216,232,713 held (+0%) $1.32 $5K +4.5% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 211,948215,924,630 held (+0%) $1.33 $282K +3.8% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 161,818216,086,448 held (+0%) $1.34 $217K +3.0% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 119,129215,665,577 held (+0%) $1.32 $157K +4.5% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 47,105215,712,682 held (+0%) $1.33 $63K +3.8% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 24,579216,111,027 held (+0%) $1.34 $33K +3.0% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 13,664216,126,448 held (+0%) $1.35 $18K +2.2% 27
Nov 20SEC Frost Gamma Investments Trust10% Owner Buy 1,757216,112,784 held (+0%) $1.35 $2K +2.2% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 198,904215,390,952 held (+0%) $1.32 $263K +4.5% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 155,496215,546,448 held (+0%) $1.32 $205K +4.5% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 66,504215,192,048 held (+0%) $1.31 $87K +5.3% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 58,160215,060,933 held (+0%) $1.29 $75K +7.0% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 36,325215,002,773 held (+0%) $1.28 $46K +7.8% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 30,082215,112,551 held (+0%) $1.30 $39K +6.2% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 21,236215,082,469 held (+0%) $1.30 $28K +6.2% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 12,993215,125,544 held (+0%) $1.31 $17K +5.3% 27
Nov 19SEC Frost Gamma Investments Trust10% Owner Buy 300215,061,233 held (+0%) $1.29 $387 +7.0% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 212,608214,779,163 held (+0%) $1.28 $272K +7.8% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 83,556214,932,875 held (+0%) $1.29 $108K +7.0% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 69,728214,848,891 held (+0%) $1.28 $89K +7.8% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 66,635214,503,083 held (+0%) $1.26 $84K +9.5% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 49,590214,436,448 held (+0%) $1.25 $62K +10.4% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 33,572214,966,448 held (+0%) $1.29 $43K +7.0% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 15,000214,564,783 held (+0%) $1.27 $19K +8.7% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 1,772214,566,555 held (+0%) $1.27 $2K +8.7% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 428214,849,319 held (+0%) $1.28 $548 +7.8% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 410214,386,858 held (+0%) $1.25 $512 +10.4% 27
Nov 18SEC Frost Gamma Investments Trust10% Owner Buy 1214,932,876 held (+0%) $1.29 $1 +7.0% 27
Oct 31SEC Phillip Md Et Al FrostCEO, Chair Buy 150,000214,386,448 held (+0%) $1.42 $213K -2.8% 84

Insiders at OPKO HEALTH, INC.

InsiderBoughtSoldLast filingScore
Frost Gamma Investments Trust10% Owner $3.0M — Nov 21, 2025 27
Phillip Md Et Al FrostCEO, Chair $213K — Oct 31, 2025 84
John A PaganelliDirector $11K — Mar 20, 2026 —

OPK stock: common questions

Are OPKO HEALTH, INC. insiders buying OPK stock?

In the past 12 months, 3 insiders reported open-market purchases of OPK worth $3.2M. The latest was Director John A Paganelli bought $11K of OPK at $1.14 — first open-market purchase in our records.

Are OPKO HEALTH, INC. insiders selling OPK stock?

0 insiders reported sales worth $0 over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is OPK's 52-week range?

Over the past year OPK has traded between $1.10 and $1.73. It last closed at $1.38 on Oct 9, 2026.