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OBIO

Orchestra BioMed Holdings (OBIO) stock: insider trades, news & valuation

Health Care · Strong buying
Close · Oct 9, 2026 $5.95 +3.8% on the day +107.3% over 12 months 52-week range $2.87 – $6.35

Share price and insider trades

OBIO closeInsider buyInsider sale
2468NovDecJan 2026FebMarAprMayJunJulAugSepOctSold $132 on 2026-04-27 · Rtw Investments, LpBought $2,494 on 2026-05-18 · Jason AryehBought $10,660 on 2026-08-26 · Darren ShermanBought $19,150 on 2026-06-01 · David P HochmanBought $20,350 on 2025-11-14 · David P HochmanBought $42,900 on 2026-03-13 · David P HochmanBought $47,900 on 2026-09-03 · David P HochmanBought $53,837 on 2026-05-15 · David P Hochman, Jason AryehSold $58,050 on 2026-06-01 · Darren ShermanSold $61,350 on 2026-08-03 · Darren ShermanSold $64,050 on 2026-07-01 · Darren ShermanSold $74,100 on 2026-09-01 · Darren ShermanBought $82,600 on 2026-05-14 · Eric S FainSold $95,400 on 2026-10-01 · Darren Sherman
Bought, 12 months$277K
Sold, 12 months$353K
Insiders buying4
Insiders selling2

Orchestra BioMed Holdings insider trading at a glance (Oct 9, 2026): in the past 12 months, 4 insiders bought $277K and 2 sold $353K of OBIO stock on the open market, including a cluster buy that began May 14, 2026.

OBIO insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q4 2025: $20K bought (1 trades)$20KQ4 2025Q1 2026: $43K bought (1 trades)$43KQ1 2026Q2 2026: $158K bought (5 trades)$158KQ2 2026: $58K sold (2 trades)Q2 2026Q3 2026: $59K bought (2 trades)$59KQ3 2026: $200K sold (3 trades)Q3 2026Q4 2026: $95K sold (1 trades)Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0$95K1
Q3 2026$59K2$200K3
Q2 2026$158K5$58K2
Q1 2026$43K1—0
Q4 2025$20K1—0

Valuation, profit and volume

Pick score 37/100
P/E (trailing)n/aSector median 24.7
Market value$358MBiotechnology
Profit margin-184.6%Revenue growth -89.5%
Volume vs. 50-day0.8×Last 5 sessions
Insiders' paper profit+$117KOn all tracked purchases +41.7%

Summary

Over the past 12 months, 4 Orchestra BioMed Holdings, Inc. insiders reported open-market purchases totaling $277K, while 2 insiders reported sales totaling $353K. The most recent cluster buy began on May 14, 2026, when 3 insiders bought a combined $136K. Among insiders with enough purchase history to measure, David P Hochman (See Remarks) has the highest Insider Score at 53. 5 of 6 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

OBIO stock news and SEC filings

Recent 8-K filings and headlines. Tone is scored from the headline wording; “Policy” marks regulatory, trade or government topics.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Oct 2SEC Darren ShermanSee Remarks Sell Plan 15,0001,119,402 held (−1%) $6.36 $95K -6.4% —
Sep 8SEC David P HochmanSee Remarks Buy 10,0001,070,746 held (+1%) $4.79 $48K +24.2% 53
Sep 2SEC Darren ShermanSee Remarks Sell Plan 15,0001,134,402 held (−1%) $4.94 $74K +20.4% —
Aug 28SEC Darren ShermanSee Remarks Buy 2,000new position $5.33 $11K +11.6% —
Aug 4SEC Darren ShermanSee Remarks Sell Plan 15,0001,154,327 held (−1%) $4.09 $61K +45.5% —
Jul 2SEC Darren ShermanSee Remarks Sell Plan 15,0001,169,327 held (−1%) $4.27 $64K +39.3% —
Jun 2SEC Darren ShermanSee Remarks Sell Plan 15,0001,184,327 held (−1%) $3.87 $58K +53.7% —
Jun 2SEC David P HochmanSee Remarks Buy 5,0001,064,029 held (+0%) $3.83 $19K +55.4% 53
May 20SEC Jason AryehDirector Buy 665118,118 held (+1%) $3.75 $2K +58.7% —
May 19SEC Jason AryehDirector Buy 8,971117,453 held (+8%) $3.90 $35K +52.6% —
May 19SEC David P HochmanSee Remarks Buy 5,0001,059,029 held (+0%) $3.77 $19K +57.8% 53
May 18SEC Eric S FainDirector Buy 20,00091,709 held (+28%) $4.13 $83K +44.1% —
Apr 29SEC Rtw Investments, Lp10% Owner Sell 329,556,063 held (−0%) $4.13 $132 +44.1% —
Mar 16SEC David P HochmanSee Remarks Buy 10,0001,086,467 held (+1%) $4.29 $43K +38.7% 53
Nov 17SEC David P HochmanSee Remarks Buy 5,000612,822 held (+1%) $4.07 $20K +46.2% 53

Insiders at Orchestra BioMed Holdings, Inc.

InsiderBoughtSoldLast filingScore
David P HochmanSee Remarks $149K — Sep 8, 2026 53
Darren ShermanSee Remarks $11K $353K Oct 2, 2026 —
Eric S FainDirector $83K — May 18, 2026 —
Jason AryehDirector $37K — May 20, 2026 —
Rtw Investments, Lp10% Owner — $132 Apr 29, 2026 —

Insider activity at other Health Care companies

Same sector, ranked by insider buying in the last 90 days.

  • SLBTSL Science Holding Ltd$10329.90B bought
  • KODKodiak Sciences Inc.$157M bought
  • ADRXADARx Pharmaceuticals, Inc.$87.7M bought
  • ATTOAttovia Therapeutics, Inc.$72.9M bought
  • MPLTMapLight Therapeutics, Inc.$65.5M bought
  • AVRAnteris Technologies Global Corp.$40.4M bought

OBIO stock: common questions

Are Orchestra BioMed Holdings, Inc. insiders buying OBIO stock?

In the past 12 months, 4 insiders reported open-market purchases of OBIO worth $277K. The latest was See Remarks David P Hochman bought $48K of OBIO at $4.79 — largest purchase by this insider in our records.

Are Orchestra BioMed Holdings, Inc. insiders selling OBIO stock?

2 insiders reported sales worth $353K over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is OBIO's 52-week range?

Over the past year OBIO has traded between $2.87 and $6.35. It last closed at $5.95 on Oct 9, 2026.