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KRYS

Krystal Biotech (KRYS) stock: insider trades, news & valuation

Heavy selling
Close · Oct 9, 2026 $331.61 +1.3% on the day +75.7% over 12 months 52-week range $181.47 – $378.15

Share price and insider trades

KRYS closeInsider buyInsider sale
100200300400NovDecJan 2026FebMarAprMayJunJulAugSepOctSold $192,500 on 2026-02-25 · Daniel JanneySold $193,903 on 2026-05-26 · John Charles ThomasSold $200,700 on 2026-03-02 · Kathryn RomanoSold $347,270 on 2026-06-25 · John Charles ThomasSold $2,133,686 on 2026-02-26 · Daniel JanneySold $3,252,845 on 2026-02-27 · Daniel JanneySold $3,401,703 on 2026-02-09 · Kathryn RomanoSold $4,953,728 on 2026-02-19 · Dino A RossiSold $8,227,934 on 2026-08-14 · Dino A RossiSold $13,159,443 on 2026-03-04 · Krish S Krishnan, Suma KrishnanSold $13,823,273 on 2026-02-24 · Daniel JanneySold $15,405,911 on 2026-06-04 · Krish S Krishnan, Suma KrishnanSold $17,966,075 on 2026-09-04 · Krish S Krishnan, Suma KrishnanSold $22,014,850 on 2025-12-04 · Krish S Krishnan, Suma Krishnan
Bought, 12 months$0
Sold, 12 months$105M
Insiders buying0
Insiders selling6

Krystal Biotech insider trading at a glance (Oct 9, 2026): in the past 12 months, 0 insiders bought $0 and 6 sold $105M of KRYS stock on the open market.

KRYS insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q4 2025: $22.0M sold (32 trades)Q4 2025Q1 2026: $41.1M sold (52 trades)Q1 2026Q2 2026: $15.9M sold (24 trades)Q2 2026Q3 2026: $26.2M sold (34 trades)Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0$26.2M34
Q2 2026—0$15.9M24
Q1 2026—0$41.1M52
Q4 2025—0$22.0M32

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day1.0×Last 5 sessions
Insiders' paper profit—On all tracked purchases —

Summary

Over the past 12 months, 0 Krystal Biotech, Inc. insiders reported open-market purchases totaling $0, while 6 insiders reported sales totaling $105M. 132 of 142 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 3,9811,362,716 held (−0%) $357.57 $1.4M -7.3% —
Sep 4SEC Suma KrishnanPresident Sell Plan 3,9621,317,390 held (−0%) $357.57 $1.4M -7.3% —
Sep 4SEC Suma KrishnanPresident Sell Plan 3,3921,310,818 held (−0%) $359.39 $1.2M -7.7% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 3,3571,356,216 held (−0%) $359.39 $1.2M -7.7% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 3,2971,366,697 held (−0%) $356.37 $1.2M -6.9% —
Sep 4SEC Suma KrishnanPresident Sell Plan 3,2671,321,352 held (−0%) $356.37 $1.2M -6.9% —
Sep 4SEC Suma KrishnanPresident Sell Plan 3,1801,314,210 held (−0%) $358.42 $1.1M -7.5% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 3,1431,359,573 held (−0%) $358.42 $1.1M -7.5% —
Sep 4SEC Suma KrishnanPresident Sell Plan 2,3201,308,498 held (−0%) $360.47 $836K -8.0% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 2,2661,353,950 held (−0%) $360.46 $817K -8.0% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 2,0101,350,726 held (−0%) $362.65 $729K -8.6% —
Sep 4SEC Suma KrishnanPresident Sell Plan 1,9921,305,264 held (−0%) $362.65 $722K -8.6% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 2,0291,369,994 held (−0%) $355.57 $721K -6.7% —
Sep 4SEC Suma KrishnanPresident Sell Plan 2,0061,324,619 held (−0%) $355.57 $713K -6.7% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 1,3581,348,795 held (−0%) $364.48 $495K -9.0% —
Sep 4SEC Suma KrishnanPresident Sell Plan 1,3291,303,370 held (−0%) $364.48 $484K -9.0% —
Sep 4SEC Suma KrishnanPresident Sell Plan 1,2421,307,256 held (−0%) $361.61 $449K -8.3% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 1,2141,352,736 held (−0%) $361.61 $439K -8.3% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 8471,347,948 held (−0%) $365.42 $310K -9.3% —
Sep 4SEC Suma KrishnanPresident Sell Plan 8261,302,544 held (−0%) $365.41 $302K -9.2% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 5731,350,153 held (−0%) $363.34 $208K -8.7% —
Sep 4SEC Suma KrishnanPresident Sell Plan 5651,304,699 held (−0%) $363.34 $205K -8.7% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 5201,372,023 held (−0%) $354.54 $184K -6.5% —
Sep 4SEC Suma KrishnanPresident Sell Plan 5201,326,625 held (−0%) $354.54 $184K -6.5% —
Sep 4SEC Krish S KrishnanCEO, President Sell Plan 4051,347,543 held (−0%) $366.56 $148K -9.5% —
Sep 4SEC Suma KrishnanPresident Sell Plan 3991,302,145 held (−0%) $366.56 $146K -9.5% —
Aug 14SEC Dino A RossiDirector Sell 7,42858,031 held (−11%) $329.60 $2.4M +0.6% —
Aug 14SEC Dino A RossiDirector Sell 5,22667,146 held (−7%) $327.39 $1.7M +1.3% —
Aug 14SEC Dino A RossiDirector Sell 4,89653,135 held (−8%) $330.36 $1.6M +0.4% —
Aug 14SEC Dino A RossiDirector Sell 3,09550,040 held (−6%) $331.43 $1.0M +0.1% —
Aug 14SEC Dino A RossiDirector Sell 2,28772,372 held (−3%) $326.60 $747K +1.5% —
Aug 14SEC Dino A RossiDirector Sell 1,68765,459 held (−3%) $328.52 $554K +0.9% —
Aug 14SEC Dino A RossiDirector Sell 34174,659 held (−0%) $325.60 $111K +1.8% —
Aug 14SEC Dino A RossiDirector Sell 4050,000 held (−0%) $333.23 $13K -0.5% —
Jun 26SEC John Charles ThomasGeneral Counsel Sell Plan 1,000 $347.27 $347K -4.5% —
Jun 5SEC Suma KrishnanPresident Sell Plan 12,7291,387,038 held (−1%) $307.81 $3.9M +7.7% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 11,4611,461,523 held (−1%) $307.68 $3.5M +7.8% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 4,8301,456,693 held (−0%) $308.47 $1.5M +7.5% —
Jun 5SEC Suma KrishnanPresident Sell Plan 3,8031,383,235 held (−0%) $308.89 $1.2M +7.4% —
Jun 5SEC Suma KrishnanPresident Sell Plan 2,8011,380,434 held (−0%) $309.95 $868K +7.0% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 2,7841,453,909 held (−0%) $309.49 $862K +7.1% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 2,6521,451,257 held (−0%) $310.43 $823K +6.8% —
Jun 5SEC Suma KrishnanPresident Sell Plan 2,0391,378,395 held (−0%) $310.94 $634K +6.6% —
Jun 5SEC Suma KrishnanPresident Sell Plan 1,3481,399,767 held (−0%) $307.09 $414K +8.0% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 9641,450,293 held (−0%) $311.36 $300K +6.5% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 6401,474,293 held (−0%) $302.24 $193K +9.7% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 5891,472,984 held (−0%) $306.33 $180K +8.3% —
Jun 5SEC Suma KrishnanPresident Sell Plan 5931,402,242 held (−0%) $302.25 $179K +9.7% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 5441,473,573 held (−0%) $304.81 $166K +8.8% —
Jun 5SEC Suma KrishnanPresident Sell Plan 4801,401,115 held (−0%) $305.87 $147K +8.4% —
Jun 5SEC Suma KrishnanPresident Sell Plan 4001,401,595 held (−0%) $304.89 $122K +8.8% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 3201,474,933 held (−0%) $300.75 $96K +10.3% —
Jun 5SEC Suma KrishnanPresident Sell Plan 3201,402,835 held (−0%) $300.75 $96K +10.3% —
Jun 5SEC Suma KrishnanPresident Sell Plan 2471,401,995 held (−0%) $303.17 $75K +9.4% —
Jun 5SEC Suma KrishnanPresident Sell Plan 2401,378,155 held (−0%) $311.65 $75K +6.4% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 1761,474,117 held (−0%) $303.17 $53K +9.4% —
Jun 5SEC Krish S KrishnanCEO, President Sell Plan 401,450,253 held (−0%) $312.23 $12K +6.2% —
May 27SEC John Charles ThomasGeneral Counsel Sell Plan 642 $302.03 $194K +9.8% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 8,7981,478,612 held (−1%) $264.85 $2.3M +25.2% —
Mar 6SEC Suma KrishnanPresident Sell Plan 6,0001,404,855 held (−0%) $265.16 $1.6M +25.1% —
Mar 6SEC Suma KrishnanPresident Sell Plan 4,8521,410,855 held (−0%) $264.64 $1.3M +25.3% —
Mar 6SEC Suma KrishnanPresident Sell Plan 3,6671,422,824 held (−0%) $260.37 $955K +27.4% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 3,1281,494,795 held (−0%) $260.49 $815K +27.3% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 2,9621,491,833 held (−0%) $261.41 $774K +26.9% —
Mar 6SEC Suma KrishnanPresident Sell Plan 2,9311,419,893 held (−0%) $261.41 $766K +26.9% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 2,4391,476,173 held (−0%) $265.59 $648K +24.9% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 2,3801,489,453 held (−0%) $262.44 $625K +26.4% —
Mar 6SEC Suma KrishnanPresident Sell Plan 2,2481,415,707 held (−0%) $263.58 $593K +25.8% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 2,0431,487,410 held (−0%) $263.70 $539K +25.8% —
Mar 6SEC Suma KrishnanPresident Sell Plan 1,9381,417,955 held (−0%) $262.35 $508K +26.4% —
Mar 6SEC Suma KrishnanPresident Sell Plan 1,7001,403,155 held (−0%) $266.42 $453K +24.5% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 1,3771,497,923 held (−0%) $259.87 $358K +27.6% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 9201,475,253 held (−0%) $266.56 $245K +24.4% —
Mar 6SEC Suma KrishnanPresident Sell Plan 6681,426,491 held (−0%) $259.61 $173K +27.7% —
Mar 6SEC Suma KrishnanPresident Sell Plan 5891,427,159 held (−0%) $258.54 $152K +28.3% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 4831,499,770 held (−0%) $257.31 $124K +28.9% —
Mar 6SEC Krish S KrishnanCEO, President Sell Plan 4701,499,300 held (−0%) $258.38 $121K +28.3% —
Mar 6SEC Suma KrishnanPresident Sell Plan 4071,427,748 held (−0%) $257.32 $105K +28.9% —
Mar 3SEC Daniel JanneyDirector Sell Plan 9,43075,666 held (−11%) $275.45 $2.6M +20.4% —
Mar 3SEC Daniel JanneyDirector Sell Plan 2,37373,293 held (−3%) $276.17 $655K +20.1% —
Mar 3SEC Kathryn RomanoChief Accounting Officer Sell Plan 75022,366 held (−3%) $267.60 $201K +23.9% —
Feb 26SEC Daniel JanneyDirector Sell Plan 11,67311,377 held (−51%) $266.97 $3.1M +24.2% —
Feb 26SEC Daniel JanneyDirector Sell Plan 8,98623,050 held (−28%) $266.18 $2.4M +24.6% —
Feb 26SEC Daniel JanneyDirector Sell Plan 6,6714,706 held (−59%) $268.04 $1.8M +23.7% —
Feb 26SEC Daniel JanneyDirector Sell Plan 5,10387,734 held (−5%) $275.28 $1.4M +20.5% —
Feb 26SEC Daniel JanneyDirector Sell Plan 4,339100,457 held (−4%) $266.62 $1.2M +24.4% —
Feb 26SEC Daniel JanneyDirector Sell Plan 3,963743 held (−84%) $268.97 $1.1M +23.3% —
Feb 26SEC Daniel JanneyDirector Sell Plan 3,55732,036 held (−10%) $265.08 $943K +25.1% —
Feb 26SEC Daniel JanneyDirector Sell Plan 2,63885,096 held (−3%) $276.32 $729K +20.0% —
Feb 26SEC Daniel JanneyDirector Sell Plan 2,42593,537 held (−3%) $274.90 $667K +20.6% —
Feb 26SEC Daniel JanneyDirector Sell Plan 1,89198,566 held (−2%) $267.37 $506K +24.0% —
Feb 26SEC Daniel JanneyDirector Sell Plan 1,73335,593 held (−5%) $264.12 $458K +25.6% —
Feb 26SEC Daniel JanneyDirector Sell Plan 1,67496,892 held (−2%) $268.67 $450K +23.4% —
Feb 26SEC Daniel JanneyDirector Sell Plan 1,604104,796 held (−2%) $265.54 $426K +24.9% —
Feb 26SEC Daniel JanneyDirector Sell Plan 93095,962 held (−1%) $269.50 $251K +23.0% —
Feb 26SEC Daniel JanneyDirector Sell Plan 900106,400 held (−1%) $264.60 $238K +25.3% —
Feb 26SEC Daniel JanneyDirector Sell Plan 70092,837 held (−1%) $275.00 $192K +20.6% —
Feb 26SEC Daniel JanneyDirector Sell Plan 56937,326 held (−2%) $262.91 $150K +26.1% —
Feb 26SEC Daniel JanneyDirector Sell Plan 373 $271.09 $101K +22.3% —
Feb 26SEC Daniel JanneyDirector Sell Plan 370373 held (−50%) $269.83 $100K +22.9% —
Feb 26SEC Daniel JanneyDirector Sell Plan 62107,300 held (−0%) $263.05 $16K +26.1% —
Feb 23SEC Dino A RossiDirector Sell 10,83478,691 held (−12%) $262.10 $2.8M +26.5% —
Feb 23SEC Dino A RossiDirector Sell 8,11689,525 held (−8%) $260.49 $2.1M +27.3% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 5,70024,118 held (−19%) $271.66 $1.5M +22.1% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 2,82421,294 held (−12%) $272.51 $770K +21.7% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 2,00029,818 held (−6%) $270.56 $541K +22.6% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 92820,366 held (−4%) $273.71 $254K +21.2% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 55219,814 held (−3%) $274.64 $152K +20.7% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 40019,414 held (−2%) $275.68 $110K +20.3% —
Feb 11SEC Kathryn RomanoChief Accounting Officer Sell Plan 9619,318 held (−0%) $277.88 $27K +19.3% —
Dec 5SEC Suma KrishnanPresident Sell Plan 10,5051,483,756 held (−1%) $221.78 $2.3M +49.5% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 10,5051,483,756 held (−1%) $221.78 $2.3M +49.5% —
Dec 5SEC Suma KrishnanPresident Sell Plan 10,4611,413,911 held (−1%) $221.82 $2.3M +49.5% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 10,4611,413,911 held (−1%) $221.82 $2.3M +49.5% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 5,6931,496,886 held (−0%) $219.55 $1.2M +51.0% —
Dec 5SEC Suma KrishnanPresident Sell Plan 5,6931,496,886 held (−0%) $219.53 $1.2M +51.1% —
Dec 5SEC Suma KrishnanPresident Sell Plan 5,4191,426,999 held (−0%) $219.68 $1.2M +51.0% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 5,4191,426,999 held (−0%) $219.68 $1.2M +51.0% —
Dec 5SEC Suma KrishnanPresident Sell Plan 3,5931,432,418 held (−0%) $218.83 $786K +51.5% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 3,5931,432,418 held (−0%) $218.83 $786K +51.5% —
Dec 5SEC Suma KrishnanPresident Sell Plan 2,6271,424,372 held (−0%) $220.52 $579K +50.4% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 2,6271,424,372 held (−0%) $220.52 $579K +50.4% —
Dec 5SEC Suma KrishnanPresident Sell Plan 2,6251,494,261 held (−0%) $220.34 $578K +50.5% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 2,6251,494,261 held (−0%) $220.34 $578K +50.5% —
Dec 5SEC Suma KrishnanPresident Sell Plan 2,5771,502,579 held (−0%) $218.72 $564K +51.6% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 2,5771,502,579 held (−0%) $218.72 $564K +51.6% —
Dec 5SEC Suma KrishnanPresident Sell Plan 1,6001,505,156 held (−0%) $217.04 $347K +52.8% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 1,6001,505,156 held (−0%) $217.04 $347K +52.8% —
Dec 5SEC Suma KrishnanPresident Sell Plan 1,4001,436,011 held (−0%) $216.97 $304K +52.8% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 1,4001,436,011 held (−0%) $216.97 $304K +52.8% —
Dec 5SEC Suma KrishnanPresident Sell Plan 9561,507,100 held (−0%) $214.28 $205K +54.8% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 9561,507,100 held (−0%) $214.28 $205K +54.8% —
Dec 5SEC Suma KrishnanPresident Sell Plan 7001,483,056 held (−0%) $222.20 $156K +49.2% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 7001,483,056 held (−0%) $222.20 $156K +49.2% —
Dec 5SEC Suma KrishnanPresident Sell Plan 7001,438,011 held (−0%) $214.25 $150K +54.8% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 7001,438,011 held (−0%) $214.25 $150K +54.8% —
Dec 5SEC Suma KrishnanPresident Sell Plan 6001,437,411 held (−0%) $215.49 $129K +53.9% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 6001,437,411 held (−0%) $215.49 $129K +53.9% —
Dec 5SEC Suma KrishnanPresident Sell Plan 3441,506,756 held (−0%) $215.48 $74K +53.9% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 3441,506,756 held (−0%) $215.48 $74K +53.9% —
Dec 5SEC Suma KrishnanPresident Sell Plan 2001,413,711 held (−0%) $222.38 $44K +49.1% —
Dec 5SEC Krish S KrishnanCEO, President Sell Plan 2001,413,711 held (−0%) $222.38 $44K +49.1% —

Insiders at Krystal Biotech, Inc.

InsiderBoughtSoldLast filingScore
Suma KrishnanPresident — $34.3M Sep 4, 2026 —
Krish S KrishnanCEO, President — $34.3M Sep 4, 2026 —
Daniel JanneyDirector — $19.4M Mar 3, 2026 —
Dino A RossiDirector — $13.2M Aug 14, 2026 —
Kathryn RomanoChief Accounting Officer — $3.6M Mar 3, 2026 —
John Charles ThomasGeneral Counsel — $541K Jun 26, 2026 —

KRYS stock: common questions

Are Krystal Biotech, Inc. insiders buying KRYS stock?

In the past 12 months, 0 insiders reported open-market purchases of KRYS worth $0.

Are Krystal Biotech, Inc. insiders selling KRYS stock?

6 insiders reported sales worth $105M over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is KRYS's 52-week range?

Over the past year KRYS has traded between $181.47 and $378.15. It last closed at $331.61 on Oct 9, 2026.