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ARWR

ARROWHEAD PHARMACEUTICALS (ARWR) stock: insider trades, news & valuation

Heavy selling
Close · Oct 9, 2026 $62.75 +3.3% on the day +74.0% over 12 months 52-week range $35.41 – $89.59

Share price and insider trades

ARWR closeInsider buyInsider sale
20406080100NovDecJan 2026FebMarAprMayJunJulAugSepOctEEarnings release filed 2025-11-25EEarnings release filed 2026-02-05EEarnings release filed 2026-05-07EEarnings release filed 2026-08-04Sold $228,334 on 2026-05-12 · Hongbo LuSold $493,412 on 2025-11-28 · Mauro FerrariSold $527,100 on 2025-12-26 · Mauro FerrariSold $641,900 on 2026-03-05 · James C HamiltonSold $750,000 on 2026-04-23 · James C HamiltonSold $861,340 on 2025-12-22 · Christopher Richard AnzaloneSold $871,703 on 2026-01-02 · Christopher Richard AnzaloneSold $934,285 on 2026-04-22 · Daniel Joseph ApelSold $991,738 on 2025-12-05 · Michael S PerrySold $1,186,600 on 2026-08-18 · Adeoye Y Olukotun, Michael S PerrySold $2,831,835 on 2025-12-19 · Adeoye Y Olukotun, Christopher Richard Anzalone, Victoria Vakiener, William D. WaddillSold $3,398,187 on 2025-12-16 · Christopher Richard AnzaloneSold $3,575,575 on 2025-12-29 · Christopher Richard AnzaloneSold $5,443,462 on 2025-12-17 · Christopher Richard AnzaloneSold $5,658,011 on 2026-01-05 · James C Hamilton, Patrick O'brienSold $8,950,615 on 2025-12-15 · Christopher Richard Anzalone
Bought, 12 months$0
Sold, 12 months$37.3M
Insiders buying0
Insiders selling10

ARROWHEAD PHARMACEUTICALS insider trading at a glance (Oct 9, 2026): in the past 12 months, 0 insiders bought $0 and 10 sold $37.3M of ARWR stock on the open market.

ARWR insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q4 2025: $27.8M sold (36 trades)Q4 2025Q1 2026: $7.2M sold (22 trades)Q1 2026Q2 2026: $1.9M sold (5 trades)Q2 2026Q3 2026: $1.2M sold (2 trades)Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0$1.2M2
Q2 2026—0$1.9M5
Q1 2026—0$7.2M22
Q4 2025—0$27.8M36

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day1.2×Last 5 sessions
Insiders' paper profit—On all tracked purchases —

Summary

Over the past 12 months, 0 ARROWHEAD PHARMACEUTICALS, INC. insiders reported open-market purchases totaling $0, while 10 insiders reported sales totaling $37.3M. Among insiders with enough purchase history to measure, Hongbo Lu (Director) has the highest Insider Score at 24. 45 of 65 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

ARWR earnings: how the stock reacted

Each quarterly results release (SEC 8-K Item 2.02), the trend before it, insider trades in the 30 days before, and the 2-day market reaction. “E” marks releases on the chart above.

Does it matter? →
Release15 days beforeInsiders, 30 days beforeReaction (2 days)Next 30 days
Aug 4, 2026 +15.8% None +1.0%S&P +1.6% -0.7%
May 7, 2026 +11.4% Sold $1.7M -8.2%S&P +0.5% +0.6%
Feb 5, 2026 +4.3% None -5.2%S&P +0.6% -7.3%
Nov 25, 2025 +12.8% None +30.4%S&P +1.6% +21.6%
Aug 7, 2025 +9.0% None +0.7%S&P +0.7% +77.1%
May 12, 2025 -2.3% None +17.3%S&P +4.0% +6.2%
Feb 10, 2025 -6.0% None -6.7%S&P +0.8% -20.2%
Nov 26, 2024 -14.2% None +39.2%S&P +0.2% -27.5%

Most companies bar insiders from trading in the weeks before results, so pre-earnings purchases are rare and often made by directors or under pre-set plans. Past reactions don't predict future ones.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Aug 20SEC Michael S PerryDirector Sell 11,600111,459 held (−9%) $87.30 $1.0M -28.1% —
Aug 20SEC Adeoye Y OlukotunDirector Sell 2,00031,600 held (−6%) $86.96 $174K -27.8% —
May 14SEC Hongbo LuDirector Sell Plan 2,97052,012 held (−5%) $76.88 $228K -18.4% 24
Apr 24SEC James C HamiltonChief Medical Officer Sell Plan 10,000226,958 held (−4%) $75.00 $750K -16.3% —
Apr 24SEC Daniel Joseph ApelCFO Sell Plan 8,730162,905 held (−5%) $71.92 $628K -12.8% —
Apr 24SEC Daniel Joseph ApelCFO Sell Plan 3,208172,792 held (−2%) $70.11 $225K -10.5% —
Apr 24SEC Daniel Joseph ApelCFO Sell Plan 1,157171,635 held (−1%) $70.45 $82K -10.9% —
Mar 9SEC James C HamiltonChief Medical Officer Sell Plan 10,000236,958 held (−4%) $64.19 $642K -2.2% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 14,792186,615 held (−7%) $63.01 $932K -0.4% —
Jan 5SEC Patrick O'brienCOO Sell Plan 13,451500,418 held (−3%) $62.96 $847K -0.3% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 12,711173,904 held (−7%) $63.95 $813K -1.9% —
Jan 5SEC Patrick O'brienCOO Sell Plan 11,842488,576 held (−2%) $63.84 $756K -1.7% —
Jan 5SEC Christopher Richard AnzaloneCEO Sell Plan 7,4163,798,510 held (−0%) $65.88 $489K -4.8% —
Jan 5SEC Patrick O'brienCOO Sell Plan 6,164513,869 held (−1%) $62.23 $384K +0.8% —
Jan 5SEC Christopher Richard AnzaloneCEO Sell Plan 5,7713,792,739 held (−0%) $66.39 $383K -5.5% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 6,090201,407 held (−3%) $62.28 $379K +0.8% —
Jan 5SEC Patrick O'brienCOO Sell Plan 5,873477,290 held (−1%) $62.91 $369K -0.3% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 4,625207,497 held (−2%) $61.24 $283K +2.5% —
Jan 5SEC Patrick O'brienCOO Sell Plan 4,368520,033 held (−1%) $61.20 $267K +2.5% —
Jan 5SEC Patrick O'brienCOO Sell Plan 2,700485,876 held (−1%) $64.44 $174K -2.6% —
Jan 5SEC Patrick O'brienCOO Sell Plan 2,336474,954 held (−0%) $64.04 $150K -2.0% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 1,200172,704 held (−1%) $64.49 $77K -2.7% —
Jan 5SEC Patrick O'brienCOO Sell Plan 900484,976 held (−0%) $66.01 $59K -4.9% —
Jan 5SEC Patrick O'brienCOO Sell Plan 900483,163 held (−0%) $62.25 $56K +0.8% —
Jan 5SEC Patrick O'brienCOO Sell Plan 600484,063 held (−0%) $61.12 $37K +2.7% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 437172,267 held (−0%) $65.97 $29K -4.9% —
Jan 5SEC Patrick O'brienCOO Sell Plan 313484,663 held (−0%) $68.00 $21K -7.7% —
Jan 5SEC James C HamiltonChief Medical Officer Sell Plan 309171,958 held (−0%) $68.00 $21K -7.7% —
Jan 5SEC Patrick O'brienCOO Sell Plan 46474,908 held (−0%) $68.00 $3K -7.7% —
Dec 30SEC Christopher Richard AnzaloneCEO Sell Plan 35,1813,822,471 held (−1%) $69.33 $2.4M -9.5% —
Dec 30SEC Christopher Richard AnzaloneCEO Sell Plan 16,5453,805,926 held (−0%) $68.69 $1.1M -8.6% —
Dec 30SEC Mauro FerrariDirector Sell Plan 7,53069,053 held (−10%) $70.00 $527K -10.4% —
Dec 23SEC Christopher Richard AnzaloneCEO Sell Plan 10,0123,808,500 held (−0%) $68.33 $684K -8.2% —
Dec 23SEC Christopher Richard AnzaloneCEO Sell Plan 8,1473,819,831 held (−0%) $68.01 $554K -7.7% —
Dec 23SEC Adeoye Y OlukotunDirector Sell Plan 6,08334,427 held (−15%) $68.04 $414K -7.8% —
Dec 23SEC William D. WaddillDirector Sell Plan 5,45157,063 held (−9%) $68.01 $371K -7.7% —
Dec 23SEC Victoria VakienerDirector Sell Plan 5,28137,683 held (−12%) $67.97 $359K -7.7% —
Dec 23SEC Christopher Richard AnzaloneCEO Sell Plan 3,9793,827,978 held (−0%) $66.67 $265K -5.9% —
Dec 23SEC Adeoye Y OlukotunDirector Sell Plan 3,09040,510 held (−7%) $66.70 $206K -5.9% —
Dec 23SEC Victoria VakienerDirector Sell Plan 2,79942,964 held (−6%) $66.63 $186K -5.8% —
Dec 23SEC Christopher Richard AnzaloneCEO Sell Plan 2,5743,805,926 held (−0%) $68.85 $177K -8.9% —
Dec 23SEC William D. WaddillDirector Sell Plan 2,41662,514 held (−4%) $66.66 $161K -5.9% —
Dec 23SEC Victoria VakienerDirector Sell Plan 1,96035,723 held (−5%) $68.39 $134K -8.2% —
Dec 23SEC Christopher Richard AnzaloneCEO Sell Plan 1,3193,818,512 held (−0%) $68.48 $90K -8.4% —
Dec 23SEC Adeoye Y OlukotunDirector Sell Plan 82733,600 held (−2%) $68.48 $57K -8.4% —
Dec 23SEC William D. WaddillDirector Sell Plan 50056,563 held (−1%) $68.53 $34K -8.4% —
Dec 19SEC Christopher Richard AnzaloneCEO Sell 46,2873,870,670 held (−1%) $63.55 $2.9M -1.3% —
Dec 19SEC Christopher Richard AnzaloneCEO Sell 35,7503,834,920 held (−1%) $64.51 $2.3M -2.7% —
Dec 19SEC Christopher Richard AnzaloneCEO Sell 1,9813,831,957 held (−0%) $66.30 $131K -5.4% —
Dec 19SEC Christopher Richard AnzaloneCEO Sell 9823,833,938 held (−0%) $65.53 $64K -4.2% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 100,5324,000,723 held (−2%) $68.67 $6.9M -8.6% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 21,3213,979,402 held (−1%) $69.28 $1.5M -9.4% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 14,0953,937,781 held (−0%) $62.12 $876K +1.0% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 10,9633,951,876 held (−0%) $61.25 $671K +2.4% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 8,1473,971,255 held (−0%) $69.96 $570K -10.3% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 8,4763,929,305 held (−0%) $62.94 $533K -0.3% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 8,4163,962,839 held (−0%) $60.51 $509K +3.7% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 6,6613,922,644 held (−0%) $64.29 $428K -2.4% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 3,2213,916,957 held (−0%) $67.87 $219K -7.5% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 1,3003,920,344 held (−0%) $65.77 $86K -4.6% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 1,0003,921,644 held (−0%) $64.96 $65K -3.4% —
Dec 16SEC Christopher Richard AnzaloneCEO Sell 1663,920,178 held (−0%) $66.77 $11K -6.0% —
Dec 9SEC Michael S PerryDirector Sell 16,250115,240 held (−12%) $61.03 $992K +2.8% —
Dec 1SEC Mauro FerrariDirector Sell 8,75068,764 held (−11%) $56.39 $493K +11.3% —
Oct 3SEC James C HamiltonChief Medical Officer Sell Plan 20,000212,122 held (−9%) $35.00 $700K +79.3% —

Insiders at ARROWHEAD PHARMACEUTICALS, INC.

InsiderBoughtSoldLast filingScore
Christopher Richard AnzaloneCEO — $24.0M Jan 5, 2026 —
James C HamiltonChief Medical Officer — $4.6M Apr 24, 2026 —
Patrick O'brienCOO — $3.1M Jan 5, 2026 —
Michael S PerryDirector — $2.0M Aug 20, 2026 —
Mauro FerrariDirector — $1.0M Dec 30, 2025 —
Daniel Joseph ApelCFO — $934K Apr 24, 2026 —
Adeoye Y OlukotunDirector — $851K Aug 20, 2026 —
Victoria VakienerDirector — $679K Dec 23, 2025 —
William D. WaddillDirector — $566K Dec 23, 2025 —
Hongbo LuDirector — $228K May 14, 2026 24

ARWR stock: common questions

Are ARROWHEAD PHARMACEUTICALS, INC. insiders buying ARWR stock?

In the past 12 months, 0 insiders reported open-market purchases of ARWR worth $0.

Are ARROWHEAD PHARMACEUTICALS, INC. insiders selling ARWR stock?

10 insiders reported sales worth $37.3M over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is ARWR's 52-week range?

Over the past year ARWR has traded between $35.41 and $89.59. It last closed at $62.75 on Oct 9, 2026.