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AGIO

AGIOS PHARMACEUTICALS (AGIO) stock: insider trades, news & valuation

Heavy selling
Close · Oct 9, 2026 $31.81 -0.3% on the day -25.0% over 12 months 52-week range $22.34 – $45.49

Share price and insider trades

AGIO closeInsider buyInsider sale
20304050NovDecJan 2026FebMarAprMayJunJulAugSepOctEEarnings release filed 2025-10-30EEarnings release filed 2026-02-12EEarnings release filed 2026-04-29EEarnings release filed 2026-07-30Sold $8,762 on 2025-10-30 · Sarah GheuensSold $8,768 on 2025-11-12 · David ScaddenSold $77,601 on 2026-01-05 · Tsveta MilanovaSold $82,260 on 2026-03-05 · Krishnan ViswanadhanSold $107,436 on 2025-11-11 · Sarah GheuensSold $145,024 on 2025-10-27 · Sarah GheuensSold $150,503 on 2026-07-01 · Sarah GheuensSold $152,255 on 2026-03-03 · Theodore James Washburn Jr.Sold $824,376 on 2025-12-30 · Brian Goff, Cecilia Jones, James William Burns, Sarah Gheuens, Tsveta MilanovaSold $914,400 on 2026-08-04 · Sarah GheuensSold $1,084,668 on 2026-03-02 · Brian Goff, Cecilia Jones, James William Burns, Sarah Gheuens, Theodore James Washburn Jr., Tsveta MilanovaSold $1,202,702 on 2026-04-02 · Brian Goff, Cecilia Jones, James William Burns, Krishnan Viswanadhan, Sarah Gheuens, Tsveta Milanova
Bought, 12 months$0
Sold, 12 months$4.8M
Insiders buying0
Insiders selling8

AGIOS PHARMACEUTICALS insider trading at a glance (Oct 9, 2026): in the past 12 months, 0 insiders bought $0 and 8 sold $4.8M of AGIO stock on the open market.

AGIO insider buying and selling by quarter

Open-market purchases (green, above the line) and sales (red, below), by trade date.

Q3 2025: $8K sold (1 trades)Q3 2025Q4 2025: $1.1M sold (11 trades)Q4 2025Q1 2026: $1.4M sold (22 trades)Q1 2026Q2 2026: $1.2M sold (7 trades)Q2 2026Q3 2026: $1.1M sold (2 trades)Q3 2026Q4 2026
QuarterBoughtPurchasesSoldSales
Q4 2026—0—0
Q3 2026—0$1.1M2
Q2 2026—0$1.2M7
Q1 2026—0$1.4M22
Q4 2025—0$1.1M11
Q3 2025—0$8K1

Valuation, profit and volume

P/E (trailing)n/aSector median —
Market value— 
Profit margin—Revenue growth —
Volume vs. 50-day1.3×Last 5 sessions
Insiders' paper profit—On all tracked purchases —

Summary

Over the past 12 months, 0 AGIOS PHARMACEUTICALS, INC. insiders reported open-market purchases totaling $0, while 8 insiders reported sales totaling $4.8M. 42 of 43 recorded sales were made under pre-scheduled Rule 10b5-1 trading plans, which are usually less informative than discretionary sales.

AGIO earnings: how the stock reacted

Each quarterly results release (SEC 8-K Item 2.02), the trend before it, insider trades in the 30 days before, and the 2-day market reaction. “E” marks releases on the chart above.

Does it matter? →
Release15 days beforeInsiders, 30 days beforeReaction (2 days)Next 30 days
Jul 30, 2026 -12.3% Sold $151K -14.3%S&P +2.4% +11.0%
Apr 29, 2026 -25.2% Sold $1.2M +12.9%S&P +1.0% +5.0%
Feb 12, 2026 -3.3% None +0.9%S&P -1.5% -0.4%
Oct 30, 2025 +4.3% Sold $161K +3.1%S&P -0.8% -32.5%
Jul 31, 2025 -4.2% None -6.8%S&P -2.0% +7.7%
May 1, 2025 +6.7% None +1.4%S&P +2.2% +6.6%
Feb 13, 2025 -2.2% None +1.2%S&P +1.1% -6.9%
Oct 31, 2024 +10.1% None -3.1%S&P -1.5% +32.4%

Most companies bar insiders from trading in the weeks before results, so pre-earnings purchases are rare and often made by directors or under pre-set plans. Past reactions don't predict future ones.

Insider transactions

Open-market purchases and sales.

Filed Insider Type Shares Price Value Since Score
Aug 6SEC Sarah GheuensChief Medical Officer Sell Plan 30,00054,645 held (−35%) $30.48 $914K +4.4% —
Jul 2SEC Sarah GheuensChief Medical Officer Sell Plan 4,00784,645 held (−5%) $37.56 $151K -15.3% —
Apr 6SEC Brian GoffCEO Sell Plan 12,472177,604 held (−7%) $34.71 $433K -8.4% —
Apr 6SEC Brian GoffCEO Sell Plan 6,596184,508 held (−3%) $34.71 $229K -8.4% —
Apr 6SEC James William BurnsGeneral Counsel Sell Plan 3,28049,306 held (−6%) $34.71 $114K -8.4% —
Apr 6SEC Tsveta MilanovaChief Commercial Officer Sell Plan 3,26246,829 held (−7%) $34.71 $113K -8.4% —
Apr 6SEC Cecilia JonesCFO Sell Plan 3,14154,998 held (−5%) $34.71 $109K -8.4% —
Apr 6SEC Krishnan ViswanadhanChief Corp Dev & Strategy Sell Plan 2,95910,282 held (−22%) $34.71 $103K -8.4% —
Apr 6SEC Sarah GheuensChief Medical Officer Sell Plan 2,94080,277 held (−4%) $34.71 $102K -8.4% —
Mar 9SEC Krishnan ViswanadhanChief Corp Dev & Strategy Sell Plan 2,9595,141 held (−37%) $27.80 $82K +14.4% —
Mar 5SEC Theodore James Washburn Jr.Principal Accounting Officer Sell 5,272868 held (−86%) $28.88 $152K +10.1% —
Mar 3SEC Brian GoffCEO Sell Plan 8,267157,466 held (−5%) $28.96 $239K +9.8% —
Mar 3SEC Brian GoffCEO Sell Plan 5,918164,548 held (−3%) $28.96 $171K +9.8% —
Mar 3SEC Brian GoffCEO Sell Plan 3,870147,733 held (−3%) $28.96 $112K +9.8% —
Mar 3SEC Sarah GheuensChief Medical Officer Sell Plan 1,68171,593 held (−2%) $28.96 $49K +9.8% —
Mar 3SEC Cecilia JonesCFO Sell Plan 1,68142,785 held (−4%) $28.96 $49K +9.8% —
Mar 3SEC James William BurnsGeneral Counsel Sell Plan 1,68138,516 held (−4%) $28.96 $49K +9.8% —
Mar 3SEC Tsveta MilanovaChief Commercial Officer Sell Plan 1,68138,778 held (−4%) $28.96 $49K +9.8% —
Mar 3SEC Cecilia JonesCFO Sell Plan 1,57349,328 held (−3%) $28.96 $46K +9.8% —
Mar 3SEC Sarah GheuensChief Medical Officer Sell Plan 1,18767,608 held (−2%) $28.96 $34K +9.8% —
Mar 3SEC Sarah GheuensChief Medical Officer Sell Plan 1,18774,406 held (−2%) $28.96 $34K +9.8% —
Mar 3SEC Cecilia JonesCFO Sell Plan 1,18745,598 held (−3%) $28.96 $34K +9.8% —
Mar 3SEC James William BurnsGeneral Counsel Sell Plan 1,18734,531 held (−3%) $28.96 $34K +9.8% —
Mar 3SEC James William BurnsGeneral Counsel Sell Plan 1,18741,329 held (−3%) $28.96 $34K +9.8% —
Mar 3SEC Tsveta MilanovaChief Commercial Officer Sell Plan 1,18741,591 held (−3%) $28.96 $34K +9.8% —
Mar 3SEC James William BurnsGeneral Counsel Sell Plan 1,16344,086 held (−3%) $28.96 $34K +9.8% —
Mar 3SEC Theodore James Washburn Jr.Principal Accounting Officer Sell Plan 7986,140 held (−12%) $28.96 $23K +9.8% —
Mar 3SEC Theodore James Washburn Jr.Principal Accounting Officer Sell Plan 7274,243 held (−15%) $28.96 $21K +9.8% —
Mar 3SEC Theodore James Washburn Jr.Principal Accounting Officer Sell Plan 6982,595 held (−21%) $28.96 $20K +9.8% —
Mar 3SEC Cecilia JonesCFO Sell Plan 59438,800 held (−2%) $28.96 $17K +9.8% —
Jan 7SEC Tsveta MilanovaChief Commercial Officer Sell Plan 2,87234,793 held (−8%) $27.02 $78K +17.7% —
Jan 2SEC Brian GoffCEO Sell Plan 12,473136,583 held (−8%) $27.09 $338K +17.4% —
Jan 2SEC Brian GoffCEO Sell Plan 6,230143,103 held (−4%) $27.09 $169K +17.4% —
Jan 2SEC Tsveta MilanovaChief Commercial Officer Sell Plan 2,93229,190 held (−9%) $27.09 $79K +17.4% —
Jan 2SEC Sarah GheuensChief Medical Officer Sell Plan 2,93264,795 held (−4%) $27.09 $79K +17.4% —
Jan 2SEC Cecilia JonesCFO Sell Plan 2,93237,394 held (−7%) $27.09 $79K +17.4% —
Jan 2SEC James William BurnsGeneral Counsel Sell Plan 2,93231,718 held (−8%) $27.09 $79K +17.4% —
Nov 14SEC David ScaddenDirector Sell Plan 20017,603 held (−1%) $43.84 $9K -27.4% —
Nov 13SEC Sarah GheuensChief Medical Officer Sell Plan 2,45461,727 held (−4%) $43.78 $107K -27.3% —
Nov 3SEC Sarah GheuensChief Medical Officer Sell Plan 20061,727 held (−0%) $43.81 $9K -27.4% —
Oct 29SEC Sarah GheuensChief Medical Officer Sell Plan 3,30261,727 held (−5%) $43.92 $145K -27.6% —
Oct 10SEC David ScaddenDirector Sell Plan 20017,603 held (−1%) $41.00 $8K -22.4% —
Oct 2SEC David ScaddenDirector Sell Plan 20017,603 held (−1%) $40.00 $8K -20.5% —

Insiders at AGIOS PHARMACEUTICALS, INC.

InsiderBoughtSoldLast filingScore
Brian GoffCEO — $1.7M Apr 6, 2026 —
Sarah GheuensChief Medical Officer — $1.6M Aug 6, 2026 —
Tsveta MilanovaChief Commercial Officer — $353K Apr 6, 2026 —
James William BurnsGeneral Counsel — $344K Apr 6, 2026 —
Cecilia JonesCFO — $334K Apr 6, 2026 —
Theodore James Washburn Jr.Principal Accounting Officer — $217K Mar 5, 2026 —
Krishnan ViswanadhanChief Corp Dev & Strategy — $185K Apr 6, 2026 —
David ScaddenDirector — $25K Nov 14, 2025 —

AGIO stock: common questions

Are AGIOS PHARMACEUTICALS, INC. insiders buying AGIO stock?

In the past 12 months, 0 insiders reported open-market purchases of AGIO worth $0.

Are AGIOS PHARMACEUTICALS, INC. insiders selling AGIO stock?

8 insiders reported sales worth $4.8M over the same period.

Where does this data come from?

Every transaction comes from Form 4 filings that insiders must submit to the SEC within two business days of a trade. We pull them from SEC EDGAR every night.

What is AGIO's 52-week range?

Over the past year AGIO has traded between $22.34 and $45.49. It last closed at $31.81 on Oct 9, 2026.